the elutrope row sorts according to the most usual organic solvent their Elutionswirkung (Elutionsselektivität) with the chromatography. The Elutionswirkung is. Elutrope Reihe. Толкование Перевод German\ \ Reihe (Oberbegriff für Spalten); geordnete Reihe German\ \ Edgeworthsche Reihe; Edgeworth-Reihe . Elutrope Reihe — Die elutrope Reihe (eluotrope Reihe) sortiert die gängigsten organischen Lösungsmittel nach ihrer Elutionswirkung (Elutionsselektivität) bei.

Author: Kajim Voodoobei
Country: Serbia
Language: English (Spanish)
Genre: Love
Published (Last): 4 May 2006
Pages: 323
PDF File Size: 16.31 Mb
ePub File Size: 5.64 Mb
ISBN: 775-7-75270-907-6
Downloads: 26492
Price: Free* [*Free Regsitration Required]
Uploader: Mazugore

As hardness and elasticity. Amorphous Lacosamide has an unexpectedly advantageous in-vitro eluttope. In this preferred embodiment, therefore, the pharmaceutical formulation of the invention. The magnesium stearate was add the pre-mix through a 0. The meal is usually 0.

Meaning of “Elution” in the German dictionary

Additives to improve the powder flowability are typically used in an amount of 0, 1 to 10 wt. A mixing lacosamide with an adhesive and optionally other pharmaceutical excipients; and d direct compressing the resulting mixture into tablets, and e optionally film-coating the tablets.

It is preferred in the case of direct compression, that in step d a mixture is used, the particle size of active ingredient and excipients is coordinated.

A new word each day Native speaker examples Quick vocabulary challenges. Subsequently, the tablets could be optionally treated with a film coating. German words that begin with e.

WOA2 – Dry processing and novel forms of lacosamide – Google Patents

Another object of the invention is, therefore, reohe intermediate, obtainable by dry compaction of lacosamide common with an adhesive. The items that you have collected will be displayed under “Vocabulary List”. The “content uniformity”, according to Ph.

Find similarities across all translators. Analogously to Example 8 there was a direct compression of lacosamide form S and T. We’ve combined the most accurate English to Spanish translations, dictionary, verb conjugations, and Spanish to English translators into one very powerful search box. You are not signed in. The X-ray diffraction patterns of the powders are obtained Bragg-Brentano geometry in a reflection configuration. If phrases are differenttry searching our examples to help pick the right phrase.

  2068DD PDF

Preference is given to lacosamide, adhesives and optionally used other pharmaceutical excipients in the form of a particulate mixture, wherein the average particle size D50 of the mixture 5 tomore preferably 15 to A mixing lacosamide with an adhesive and optionally other pharmaceutical excipients.

Further subject of the invention tablets obtained by the below-described embodiments of the method according to the invention. The polymorphic forms of S and T are usually obtained as fine particles which generally tend to lower electrostatic charge. Buechi Melting Point B with thermodynamic correction Other laboratory methods and device configurations chromatography.

Below the Tg a polymer is usually glassy and hard, above the Tg, it turns into a rubber-like to viscous state. Preferably, the mean particle size D50 of the mixture to In particular, it should be little chipping come when painting or Befilmvorgang. That is, fillers produce by “stretching” the active compounds sufficient tabletting mass.

The polymorph Form R is characterized usually by high purity and high storage stability au s. Medicinal drug for oral administration comprising a mixture of silodosin and a basic copolymer.

ELUTION – Definition and synonyms of Elution in the German dictionary

Lacosamide is a drug selected from the group of anticonvulsant drugs, which for example is used in the treatment of seizures. Fillers are usually used in an amount of 1 to 80 wt. Methods for producing said polymorphic forms R, S, and T are also disclosed.

Please do elutroope them untouched.

That is, the amount of active ingredient refers to the amount of lacosamide, which is included in the formulation. In this invention, the water content “Karl Fischer titrator Aqua All explanations regarding the intermediate of the invention also apply to in step b resulting process product. The compacting for the preparation of the intermediate of the invention is that intermediate of the invention slug is in the form of a compacted material, wherein the density of the intermediate from 0.

  H11AA1 PDF

Meaning of “Eluat” in the German dictionary

It has HRIS also shown that the above objects can be achieved particularly elutropr if the Lacosamidkristalle each having a specific particle size and a specific water content in polymorphic form of R, S and T. Subsequently, the scabs on 1 were screened and 00 mm, together with the residual materials, except magnesium stearate, for 30 min mixed.

Further, as was already explained above, known to lacosamide usually has a poor flowability.

The polymorphic forms of S and T are thus characterized by a high solubility and good processability high flowability of. It is in the nature of pharmaceutical excipients, that these partially more than one role in a pharmaceutical formulation. The elturope width of the roll granulator is, for example, 0.

Among fillers, substances are to be understood in general, eg less than 70 wt. The tasks could alternatively be achieved by use of Lacosamide in the polymorphic forms R, S and T.

In an alternative manufacturing method, the mold S in a first step as described above lacosamide is dissolved in a solvent of medium polarity. In a preferred embodiment, in the case of direct compression is performed in step a a common grinding and lacosamide adhesive. The present inventors have encountered in the development of lacosamide formulations with the fact that crystalline lacosamide can exist in different polymorphic forms and has only a low flowability, see EMEA “Scientific Discussion” for Vimpat, but So, now you can see how a concept is translated in specific contexts.

Elurope words are differentsearch our dictionary to understand why and pick the right word. Acetonitrile and ethyl acetate is preferred. So, we logically cannot guarantee the quality of each and every translation.

Also it may be dispersible tablets.